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Abstract #4864

THE CHALLENGE OF TRACTOGRAPHY APPLIED TO CRANIAL NERVES: OUR EXPERIENCE ON DESIGN OF REGIONS OF INTEREST

Timothée Jacquesson1,2,3, François Cotton1,4, Justine Bosc1, Moncef Berhouma1,2, Emmanuel Jouanneau2, Arnaud Attye5, and Carole Frindel1

1CREATIS UMR 5220, U1206, University of Lyon, Lyon, France, 2Skull Base Multi-disciplinary Unit, Hospices Civils de Lyon, Lyon, France, 3Department of Anatomy, University of Lyon, Lyon, France, 4Department of Radiology, Hospices Civils de Lyon, Lyon, France, 5Department of Radiology, Grenoble University Hospital, Grenoble, France

Recent studies have demonstrated diffusion tensor imaging tractography of cranial nerves (CNs). Spatial and angular resolution, however, is limited with this imaging technique. In this study, we reported our experience in CNs tractography detailing the influence of ROI design. We demonstrated that understanding in detail the key role of ROI design and its influence helps to provide coherent tracts. We expect this work to enable a more reliable CNs tractography and made it a useful tool for surgical planning of complex skull base tumors.

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