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Abstract #4950

Military TBI Patients Demonstrate Increased Cerebral Venous Volume Using Quantitative Susceptibility Mapping

Wei Liu1,2, Gerard Riedy1, Ping-Hong Yeh1,2, Dominic E Nathan1,2, Chihwa Song1, Grant H Bonavia1, and John Ollinger1

1National Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD, United States, 2The NorthTide Group, LLC, Sterling, VA, United States

Cerebral venous volume above the lateral ventricle was analyzed using quantitative susceptibility mapping in patients with severe (n = 7), moderate (n = 21) and mild (n = 27 for blast and n = 19 for nonblast) TBI. Severe and moderate TBI patients both demonstrated increased venous volume compared to control subjects without history of TBI. Blast injured mild TBI patients also showed increased venous volume compared to the control subjects. These results suggest that microvascular injury may present in TBI patients and blast related injury might have a more pronounced impact on the venous system.

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