The objective of this study was to determine the neurochemical biomarkers for mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) among members of the military. A sample of 100 participants were assigned to each cohort (mTBI only, PTSD only, mTBI and PTSD, military control, and civilian control). Analysis of metabolite concentrations in the mTBI and PTSD cohorts showed significant metabolite difference across 3 voxels in the brain (posterior cingulate gyrus (PCG), anterior cingulate cortex (ACC), and posterior white matter (PWM)), indicating that magnetic resonance spectroscopy provides objective biomarkers for distinguishing these conditions.
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