Abstract #5004

GRE Phase Contrast of the Brain at Ultra-Short TE in Patients with Multiple Sclerosis

Hongjiang Wei¹, Peng Cao², Roland Henry², Peder Larson², and Chunlei Liu¹

¹EECS, University of California, Berkeley, Berkeley, CA, United States, ²Radiology and Biomedical Imaging, UCSF School of Medicine, San Francisco, CA, United States

The purpose of this study was to determine whether gradient-echo proton images of the brain exhibit any phase contrast at UTE and whether this contrast can be used to improve the characterization of tissue microstructure in the brain. Our data demonstrated that UTE images of the brain can attain strong phase contrast even at a TE of 226ms by using off-resonance RF pulses for selective saturation. UTE phase in an MS patient shows a strong contrast with surrounding white matters.

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