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Abstract #5048

T2 Relaxometry of Cartilage and Meniscus and Semi-Quantitative Assessment of the Osteoarthritic Knee using a fast 3D Quantitative DESS Scan

Susanne Eijgenraam1, Akshay Chaudhari2, Max Reijman3, Edwin Oei1, Brian Hargreaves2, and Garry Gold2

1Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, Netherlands, 2Stanford University Medical Center, Stanford, CA, United States, 3Orthopedic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands

In this study, we investigated quantitative and semi-quantitative MR imaging biomarkers of knee OA, obtained with a 5-minute DESS sequence, in increasing stages of knee OA. 54 patients were included: 20 patients with no knee OA, 18 patients with mild knee OA and 16 patients with moderate knee OA. All patients were scanned using DESS and a routine clinical knee MRI protocol. Simultaneous quantitative T2 and morphological assessment of cartilage and meniscus with a 5-minute DESS-sequence showed consistent outcomes with increasing stages of degeneration, making this sequence a useful tool for OA research.

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