Abstract #5048

T2 Relaxometry of Cartilage and Meniscus and Semi-Quantitative Assessment of the Osteoarthritic Knee using a fast 3D Quantitative DESS Scan

Susanne Eijgenraam¹, Akshay Chaudhari², Max Reijman³, Edwin Oei¹, Brian Hargreaves², and Garry Gold²

¹Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, Netherlands, ²Stanford University Medical Center, Stanford, CA, United States, ³Orthopedic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands

In this study, we investigated quantitative and semi-quantitative MR imaging biomarkers of knee OA, obtained with a 5-minute DESS sequence, in increasing stages of knee OA. 54 patients were included: 20 patients with no knee OA, 18 patients with mild knee OA and 16 patients with moderate knee OA. All patients were scanned using DESS and a routine clinical knee MRI protocol. Simultaneous quantitative T2 and morphological assessment of cartilage and meniscus with a 5-minute DESS-sequence showed consistent outcomes with increasing stages of degeneration, making this sequence a useful tool for OA research.

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