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Abstract #5288

Utility of Combination Image of T2-weighted and FLAIR using Synthetic MRI for Improved Lesion Contrast in Multiple Sclerosis

Yasuhiro Fujiwara1, Yumi Inoue2, Masayuki Kanamoto3, Shota Ishida3, Toshiki Adachi3, and Hirohiko Kimura4

1Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 2Schoo of Health Sciences, Kumamoto University, Kumamoto, Japan, 3Radiological Center, University of Fukui Hospital, Fukui, Japan, 4Department of Radiology, University of Fukui, Fukui, Japan

To improve multiple sclerosis plaque, we attempted to produce Synthetic FLAIR3 (SyFLAIR3) combined from FLAIR and T2WI using Synthetic MRI. The purpose of this study was to determine optimal contrast weighting for SyFLAIR3 and to evaluate whether the SyFLAIR3 can improve the T2 contrast on WM. To effectively suppress CSF signal for SyFLAIR3, it was necessary to optimize the combination of TE for T2WI and FLAIR. The optimized SyFLAIR3 using Synthetic MRI makes it possible to improve contrast in MS lesion.

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