Abstract #5290

Quantitative MT (qMT) imaging of the Whole Brain: Conventional 3D MT vs. 3D EP-vfMT methods

Se-Hong Oh^1,2, Dongmyung Shin³, Ken Sakaie², Daniel Ontaneda⁴, and Mark J. Lowe²

¹Department of Biomedical Engineering, Hankuk University of Foreign Studies, Yong-In, Republic of Korea, ²Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, ³Department of Electrical and computer engineering, Seoul National University, Seoul, Republic of Korea, ⁴Mellen Center, Cleveland Clinic Foundation, Cleveland, OH, United States

In this study, the whole brain qMT map from conventional MT imaging was compared with that from a newly proposed method, Segmented EPI readout Variable Flip angle Magnetization Transfer (EP-vfMT). The voxel-wise correlation shows a high correlation between the two maps. Compared to the conventional MT method, EP-vfMT provides similar image quality with good reproducibility. It also covers a whole brain volume in a much reduced scan time.

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