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Abstract #5290

Quantitative MT (qMT) imaging of the Whole Brain: Conventional 3D MT vs. 3D EP-vfMT methods

Se-Hong Oh1,2, Dongmyung Shin3, Ken Sakaie2, Daniel Ontaneda4, and Mark J. Lowe2

1Department of Biomedical Engineering, Hankuk University of Foreign Studies, Yong-In, Republic of Korea, 2Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, 3Department of Electrical and computer engineering, Seoul National University, Seoul, Republic of Korea, 4Mellen Center, Cleveland Clinic Foundation, Cleveland, OH, United States

In this study, the whole brain qMT map from conventional MT imaging was compared with that from a newly proposed method, Segmented EPI readout Variable Flip angle Magnetization Transfer (EP-vfMT). The voxel-wise correlation shows a high correlation between the two maps. Compared to the conventional MT method, EP-vfMT provides similar image quality with good reproducibility. It also covers a whole brain volume in a much reduced scan time.

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