Electroconvulsive therapy is a safe, rapid-acting antidepressant treatment that has consistently been associated with grey matter (GM) volume increase, primarily in the medial temporal lobe (MTL). Here we replicate and extend previous studies by demonstrating substantial surface area and local displacement changes in subcortical and MTL GM one week following the last ECT treatment in 70 patients with late-life depression. We report new data on ECT induced thalamus shape changes, and demonstrate that whilst the number of ECT treatments correlates positively with the degree of medial temporal GM surface area increase, this is not associated with clinical improvement in mood.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords