Abstract #5427

White Matter Integrity in Adolescents with Attention Deficit Hyperactivity Disorder with Comorbid Bipolar Disorder assessed by Tract Based Spatial Statistics

Arzu Ceylan Has¹, Mahmut Mujdeci², Gokce Nur Say², Hediye Pinar Gunbey³, Nilufer Okumus⁴, Yusuf Karaer⁵, Halime Tuna Cak Esen⁵, Ozlem Yildiz Gundogdu⁴, Rahsan Gocmen⁶, and Yonca Anik⁷

¹National Magnetic Resonance Research Center (UMRAM), Bilkent University, Ankara, Turkey, ²Department of Child and Adolescents Psychiatry, On Dokuz Mayis University, Samsun, Turkey, ³Department of Radiology, On Dokuz Mayis University, Samsun, Turkey, ⁴Department of Child and Adolescents Psychiatry, Kocaeli University, Kocaeli, Turkey, ⁵Department of Child and Adolescents Psychiatry, Hacettepe University, Ankara, Turkey, ⁶Department of Radiology, Hacettepe University, Ankara, Turkey, ⁷Department of Radiology, Kocaeli University, Kocaeli, Turkey

White matter (WM) integrity is an important factor for the pathophysiology of attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) in adolescents. In this study, we hypothesized that adolescents with attention deficit hyperactivity disorder with comorbid bipolar disorder (ADHD+BD) would yield different pattern and extent of WM abnormalities than ADHD and BD. Sixty adolescents were categorized into four groups as ADHD, BD, ADHD+BD and healthy controls. The comparative diffusion tensor imaging analyses were performed between each patient group and healthy controls. Adolescents with ADHD+BD displayed different pattern and extent of WM abnormalities than ADHD and BD revealed by tract-based spatial statistics.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.