Abstract #5502

3D Steady-State Inhomogeneous Magnetization Transfer (ihMT) Gradient Echo Sequence for Spinal Cord Imaging at 3T

Ece Ercan¹, Marco C. Pinho^1,2, Gopal Varma³, Ivan E. Dimitrov^2,4, Xinzeng Wang¹, Ananth J. Madhuranthakam^1,2, Robert E. Lenkinski^1,2, and Elena Vinogradov^1,2

¹Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ²Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, ³Radiology, Division of MR Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, ⁴Philips Healthcare, Gainesville, FL, United States

Inhomogeneous magnetization transfer (ihMT) is an enhanced magnetization transfer method, which is sensitive to dipolar couplings in white matter. Current spinal cord applications of ihMT use long saturation followed by single-slice acquisitions. As an alternative to this implementation, in our study we implemented and optimized a pulsed ihMT-prepared 3D gradient echo sequence for a larger coverage of spinal cord. The in vivo ihMT results from cervical spinal cord demonstrate potential for future applications of the ihMT in the spinal cord.

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