QUASAR ASL is an arterial transit time insensitive perfusion imaging technique which can be used to unravel hemodynamic patterns. This study evaluates cerebral perfusion hemodynamics using QUASAR in patients with type-2 diabetes mellitus (T2DM) and normoglycemic controls. In addition to standard perfusion parameters, multiple metrics were extracted from five QUASAR-derived curves pre and post acetazolamide injection both globally and locally, from regions adjacent to major vascular territories. Following feature reduction, a binary classification task was performed (normoglycemia vs. T2DM). Necessary steps were undertaken to reassure that the observed results were not due to overfitting. The achieved classification accuracy was 95%.
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