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Abstract #0003

Improved lung imaging and oxygen enhancement at 0.55T

Ipshita Bhattacharya1, Rajiv Ramasawmy1, Delaney R McGuirt1, Christine Mancini1, Robert J Lederman1, Joel Moss1, Marcus Y Chen1, Robert S Balaban1, and Adrienne E Campbell-Washburn1

1National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States

Signal dephasing at high field and low proton density, has limited the use of MRI for lung imaging. We revisit the problem, using a low field (0.55T) scanner which, due to low magnetic susceptibility, improves the signal at air-tissue boundaries like lung. Moreover, because oxygen has increased r1 relaxativity at low field, oxygen inhalation can be used to significantly increase lung signal at 0.55T. Combined, these advantages makes lung MRI lucrative at low field. In this abstract we demonstrate oxygen-enhanced lung MRI at 0.55T in healthy volunteers and Lymphangioleiomyomatosis (LAM) patients.

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