Functional lung imaging via inhaled hyperpolarized 129Xe MRI has been shown to provide sensitive regional maps of ventilation and gas-exchange. Traditionally, ventilation images are acquired via standard Cartesian or less commonly radial sequences. Previously reported results have shown promise for 2D-spiral sequences with increased SNR and/or shorter acquisition lengths. In this study, a 3D-spiral sequence (FLORET) was implemented and compared to Cartesian, radial, and 2D-spiral acquisition techniques. This is the first implementation and comparison of a 3D-spiral UTE technique to acquire hyperpolarized gas images.
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