Abstract #0077

Connectivity Reorganization after Repetitive Mild Traumatic Brain Injury is Impact Site Associated

Yu-Chieh Jill Kao^1,2,3, Chia-Feng Lu⁴, Bao-Yu Hsieh⁵, and Cheng-Yu Chen^1,2,3,6

¹Neuroscience Research Center, Taipei Medical University, Taipei, Taiwan, ²Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ³Translational Imaging Research Center, Taipei Medical University Hospital, Taipei, Taiwan, ⁴Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ⁵Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, ⁶Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan

Different degrees of functional reorganization associated with impact site was unraveled in the acute and chronic phase in the well-controlled animal model of repetitive mTBI. This is the first demonstration of impact site-dependent connectivity alteration without significant parenchymal damage after mTBI in rats.

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