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Abstract #0126

Quantitative multiparametric mapping assessment of the rat brain through adolescence into adulthood

Stephen Sawiak1,2, Bianca Jupp3, Jolyon A Jones3, Peter Zhukovsky3, and Jeffrey W Dalley3

1Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom, 2Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom, 3University of Cambridge, Cambridge, United Kingdom

We demonstrate high-resolution quantitative multiparametric mapping in the rat: scanning animals before and after adolescence and comparing them to the adult. We produce maps sensitive to myelin signal throughout the brain that complement volumetric information normally used in developmental studies. The aim is to better exploit models of neuropsychiatric disorders, particularly those with developmental components.

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