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Abstract #0127

Multi-vendor multi-site T1ρ and T2 quantification of knee cartilage

Jeehun Kim1, Kenji Mamoto1, Richard Lartey1, Kaipin Xu1, Matthew Tanaka2, Emma Bahroos2, Carl S. Winalski1, Thomas M. Link2, Peter A. Hardy3, Qi Peng4, Angie Botto-van Bemden5, Kecheng Liu6, Robert D. Peters7, Can Wu8, and Xiaojuan Li1

1Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 2University of California, San Francisco (UCSF), San Francisco, CA, United States, 3University of Kentucky, Lexington, KY, United States, 4Albert Einstein College of Medicine, Bronx, NY, United States, 5Arthritis Foundation, Atlanta, GA, United States, 6Siemens Medical Solution Inc, Malvern, PA, United States, 7GE Healthcare, Milwaukee, WI, United States, 8Philips Healthcare, Andover, MA, United States

T and T2 relaxation times are promising biomarkers for early detection of osteoarthritis due to its sensitivity to cartilage degeneration. Good reliability is essential for these quantitative measures to be widely applicable in clinical trials. We implemented MAPSS T and T2 imaging on multiple platforms (Siemens, GE, Philips) and evaluated the intra-site repeatability and inter-site reproducibility of T and T2 data in a multi-site multi-vendor setting.

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