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Abstract #0777

Myocardial Infarct Characterization using Relaxation along Fictitious Field in the nth Rotating Frame

Amir Mirmojarabian1, Esa Liukkonen2, Victor Casula1, Mikko J Nissi1,3, Lauri Ahvenjärvi2, Juhani Junttila4, and Timo Liimatainen1,2

1Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 2Department of Radiology, Oulu University Hospital, Oulu, Finland, 3Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, 4Department of Cardiology, Oulu University Hospital, Oulu, Finland

Based on the previous promising relaxation along fictitious field in nth frame (RAFFn) findings in myocardial infarct mouse model at 9.4 T, we adjusted RAFFn measurement to standard clinical 1.5 T scanner with γB1 = 500 Hz. We demonstrate with five myocardial infarct patients that fitted steady state from RAFF2 and RAFF3 weighted images can separate the infarct from remote myocardium using clinical main and RF fields. We also demonstrate association between RAFF3 steady state and extra cellular volume that is calculated based on pre and post contrast T1 maps and hematocrit.

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