Abstract #0777

Myocardial Infarct Characterization using Relaxation along Fictitious Field in the nth Rotating Frame

Amir Mirmojarabian¹, Esa Liukkonen², Victor Casula¹, Mikko J Nissi^1,3, Lauri Ahvenjärvi², Juhani Junttila⁴, and Timo Liimatainen^1,2

¹Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, ²Department of Radiology, Oulu University Hospital, Oulu, Finland, ³Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, ⁴Department of Cardiology, Oulu University Hospital, Oulu, Finland

Based on the previous promising relaxation along fictitious field in n^th frame (RAFFn) findings in myocardial infarct mouse model at 9.4 T, we adjusted RAFFn measurement to standard clinical 1.5 T scanner with γB₁ = 500 Hz. We demonstrate with five myocardial infarct patients that fitted steady state from RAFF2 and RAFF3 weighted images can separate the infarct from remote myocardium using clinical main and RF fields. We also demonstrate association between RAFF3 steady state and extra cellular volume that is calculated based on pre and post contrast T₁ maps and hematocrit.

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