Diffusion tensor imaging has been utilized to study the impact of cancer treatment on white matter microstructure in paediatric brain tumour survivors. We utilized magnetization transfer imaging (MTI), which provides more specific information on myelin, along with DTI, to determine if treatment for paediatric brain tumours has specific or non-specific impacts on white matter structure. When compared to their healthy counterparts, children treated for brain tumours exhibit decreased anisotropy and increased diffusion metrics without any significant differences in MT. This suggests treatment may impact fiber organization rather than myelin structure in this patient population.
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