Abstract #1203

Fast hybrid IVIM-DK imaging in the kidney

Kao-Lang Liu¹, Kuo-How Huang², Chin-Chen Chang¹, and Wen-Chau Wu^1,3,4

¹Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan, ²Department of Urology, National Taiwan University Hospital, Taipei, Taiwan, ³Graduate Institute of Medical Device and Imaging, National Taiwan University, Taipei, Taiwan, ⁴Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan

The application of intravoxel incoherent motion (IVIM) and diffusion kurtosis (DK) MRI has been hindered largely by the long scan time required to sample over multiple b-values and/or diffusion-encoding directions. In this study, a novel method is described to expedite hybrid IVIM-DK imaging in the kidneys. Scan time is reduced by acquiring minimally-required non-zero b-values, while index calculation is made more time-efficient by using closed-form solution to replace nonlinear fitting. Experimental data demonstrated feasibility with b = 0/400/800/1600 s/mm². Measurement variability was found greater among diffusion-encoding directions than between repeats, suggesting non-trivial structural anisotropy in the kidneys.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.