Functional MRI of the kidneys is a promising tool for diagnosis, prognosis and treatment monitoring in kidney disease, but there is urgent need for technical validation of renal MRI parameters, including reproducibility. We performed repeated measurements of a multi-parametric renal MRI protocol, including oxygenation, diffusion, perfusion and relaxometry, in healthy volunteers at 3T. This allows for mutual comparison of parameters in terms of reproducibility. As a first step to large scale studies, we have determined reproducibility and shown feasibility of renal quantitative, multi-parametric MRI within a clinically acceptable scan time.
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