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Abstract #1362

Percentage fat fraction in magnetic resonance imaging: an upgrade of the osteoporosis detecting parameter

Rong Chang1, Xiaowen Ma1, and Ming Zhang2

1Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'anļ¼ŒShaanxi, China, 2First Affiliated Hospital, Medical College Xi'an Jiaotong University, Xi'an, Shaanxi, China

The diagnosis of osteoporosis (OP) is mainly based on orthopedic imaging approaches. The percentage fat fraction (FF%) in magnetic resonance imaging (MRI) has the potential to be used to predict and diagnose OP. In both 1-H MRS and mDIXON Quant MRI, the FF% exhibited a negative correlation with BMD. Among the three groups, the OP patients had significantly higher FF% compared to healthy subjects. In addition, the FF% according to mDIXON exhibited a positive correlation with age, and BMD showed a negative linear relationship with age. Furthermore, females had a higher FF% level compared to males. Furthermore, height was correlated with BMD but not FF%. MRI investigation (especially the FF% according to the mDIXON Quant imaging system) is useful in OP assessment. Parameters including gender and age, as well as height, are important factors for OP prediction and diagnosis.

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