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Abstract #1740

Texture analysis Using Hepatobiliary Phase Gadoxetic-acid MRI for the Detection of Liver Allograft Fibrosis

Miriam Hulkower1,2, Sara Lewis1,2, Nicholas Vountsinas1, Xing Chin1, Priyanka Kadaba1, Andrew Lee1, Ayushi Singh1, Joseph Song1, Stefanie Hectors1,2, Octavia Bane1,2, Paul Kennedy1,2, Juan Putra3, Swan Thung3, Thomas Schiano4, Maria Isabel Fiel3, and Bachir Taouli1,2

1Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 4Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States

The goal of our study was to assess the value of qualitative and quantitative texture features on gadoxetic-acid enhanced MRI compared to blood tests for the detection of liver allograft fibrosis. We found that quantitative texture analysis and laboratory FIB-4 score exhibited complementary information for prediction of fibrosis stage, while qualitative MRI features were only valuable for identifying advanced fibrosis/cirrhosis.

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