Abstract #1754

Correlation between susceptibility, R2* and PDFF in liver

Ramin Jafari^1,2, Adrija Mamidipalli³, Walter Henderson³, Gavin Hamilton³, Pascal Spencemille², and Mark Bydder⁴

¹Meinig School of Biomedical Engineering, Cornell University, New York, NY, United States, ²Department of Radiology, Weill Medical College of Cornell University, New York, NY, United States, ³Radiology, UCSD, San Diego, CA, United States, ⁴Radiological Sciences, UCLA, Los Angeles, CA, United States

A susceptibility difference between the water and fat components in liver should give rise to a linear increase in R2* with proton density fat fraction (PDFF). This is observed empirically although the value of the susceptibility difference is subject to variability (from ~0 ppm to 0.75ppm). The present abstract aims to measure the susceptibility difference directly by measuring liver susceptibility as a function of the PDFF in patients with fatty liver.

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