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Abstract #1754

Correlation between susceptibility, R2* and PDFF in liver

Ramin Jafari1,2, Adrija Mamidipalli3, Walter Henderson3, Gavin Hamilton3, Pascal Spencemille2, and Mark Bydder4

1Meinig School of Biomedical Engineering, Cornell University, New York, NY, United States, 2Department of Radiology, Weill Medical College of Cornell University, New York, NY, United States, 3Radiology, UCSD, San Diego, CA, United States, 4Radiological Sciences, UCLA, Los Angeles, CA, United States

A susceptibility difference between the water and fat components in liver should give rise to a linear increase in R2* with proton density fat fraction (PDFF). This is observed empirically although the value of the susceptibility difference is subject to variability (from ~0 ppm to 0.75ppm). The present abstract aims to measure the susceptibility difference directly by measuring liver susceptibility as a function of the PDFF in patients with fatty liver.

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