This study aimed to demonstrate the feasibility and accuracy of magnetic resonance imaging multi-echo Dixon rapid liver fat quantitative analysis for liver fat content in the obese patients. In the first of our study, we performed liver scan on 17 obese patients using multi-echo Dixon rapid liver fat quantification technique and then we re-measured the entire liver fat content by previous method manually drawing ROIs on each liver segment. The Bland-Altman plots and Pearson correlation analysis were performed on the quantitative results of the above two methods. There statistical analysis showed there were good consistence and highly correlated with the two methods. We found the multi-echo Dixon rapid liver fat quantitative can simply, feasibility and accurately assess the liver fat content in the patients with obese .