Abstract #1880

Comparison of quantified pulmonary blood flow using phase-resolved functional lung (PREFUL) MRI and dynamic contrast enhanced MRI in COPD, CF and CTEPH patients

Lea Behrendt^1,2, Andreas Voskrebenzev^1,2, Filip Klimes^1,2, Marcel Gutberlet^1,2, Till Kaireit^1,2, Tawfik Moher Alsady^1,2, Frank Wacker^1,2, and Jens Vogel-Claussen^1,2

¹Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, ²Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany

Phase-resolved functional lung (PREFUL) MRI is a very promising method for contrast agent free pulmonary perfusion measurement in free breathing. Still a large-scale validation of quantified pulmonary blood flow (PBF_PREFUL) with the current gold standard PBF_DCE derived by dynamic contrast enhanced (DCE) MRI is missing. Therefore, 52 patients with COPD, CF and CTEPH were included in this study and the correlations for PBF_PREFUL and PBF_DCE were assessed. Except for CTEPH, strong and moderate correlations were found. Low or no correlation can be explained by respiratory motion (DCE) and perfusion delay (PREFUL).

This abstract and the presentation materials are available to members only; a login is required.

Join Here