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Abstract #2022

Quantitative Multiparametric Myocardial Evaluation in Hypertrophic Cardiomyopathy using Cardiac Magnetic Resonance Fingerprinting: Comparison to Conventional Cardiac Relaxometry.

Bernd J. Wintersperger1, Jesse Hamilton2, Christian Houbois1, Yuchi Liu2, Kate Hanneman1, Nicole Seiberlich2, and Marshall Sussman1

1Department of Medical Imaging, University of Toronto, Toronto, ON, Canada, 2Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States

Multiparametric quantitative myocardial tissue characterization has demonstrated promising results in the differential diagnosis of non-ischemic cardiomyopathies. While conventional cardiac relaxometry techniques employ various different sequence approaches with subsequent fitting data fitting, library based cardiac magnetic resonance fingerprinting (cMRF) enables single breath-hold multi-contrast acquisitions. This investigation into the comparison of cMRF with standard modified Look-Locker inversion recovery (MOLLI) T1 mapping and its derived parameters and T2-prep FLASH T2 mapping demonstrated promising results in the assessment of patients with hypertrophic cardiomyopathies.

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