Abstract #2022

Quantitative Multiparametric Myocardial Evaluation in Hypertrophic Cardiomyopathy using Cardiac Magnetic Resonance Fingerprinting: Comparison to Conventional Cardiac Relaxometry.

Bernd J. Wintersperger¹, Jesse Hamilton², Christian Houbois¹, Yuchi Liu², Kate Hanneman¹, Nicole Seiberlich², and Marshall Sussman¹

¹Department of Medical Imaging, University of Toronto, Toronto, ON, Canada, ²Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States

Multiparametric quantitative myocardial tissue characterization has demonstrated promising results in the differential diagnosis of non-ischemic cardiomyopathies. While conventional cardiac relaxometry techniques employ various different sequence approaches with subsequent fitting data fitting, library based cardiac magnetic resonance fingerprinting (cMRF) enables single breath-hold multi-contrast acquisitions. This investigation into the comparison of cMRF with standard modified Look-Locker inversion recovery (MOLLI) T1 mapping and its derived parameters and T2-prep FLASH T2 mapping demonstrated promising results in the assessment of patients with hypertrophic cardiomyopathies.

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