Abstract #2023

Combined SAturation recovery and Variable flip Angle (SAVA) for free-breathing high-resolution three-dimensional cardiovascular magnetic resonance T1 mapping at 3T

Rui Guo¹, zhensen chen^1,2, Dongyue Si¹, Daniel A. Herzka^3,4, jianwen luo¹, and Hanyan Ding¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, ²Vascular Imaging Laboratory, Department of Radiology, Vascular Imaging Laboratory, Seattle, WA, United States, ³National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, ⁴Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, United States

Cardiac Magnetic Resonance T₁ mapping enables quantitative characterization of myocardium, which appeals huge attention from clinic. In this work, we proposed a free-breathing high-resolution three-dimensional (3D) T₁ mapping sequence. By using variable flip Angle technique for readouts and saturation-recovery preparation for T₁ weightings, the proposed sequence is highly efficient in acquisition of all volumes, including the one at the equilibrium of the longitudinal magnetization. Whole-heart pre- and post-contrast homogeneous T₁ maps at an imaging resolution 1.25×1.25×8 mm³ were successfully obtained within 10 minutes in healthy volunteers. After rigid registration, 3D Extracellular Volume maps were eventually achieved.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.