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Abstract #2211

Improved infarct scar imaging and scar classification using native T1ρ-mapping

Maximilian Gram1,2, Daniel Gensler1,3, Michael Seethaler2,3, Anton Xu2,3, Peter Michael Jakob2, and Peter Nordbeck1,3

1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, 2Experimental Physics V, University of Würzburg, Würzburg, Germany, 3Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany

Myocardial mapping techniques are known to provide new diagnostic possibilities for morphological and functional information including accurate tissue classification for several diseases. However, without the use of contrast agents, the differentiation between healthy and diseased tissue is hardly possible. In the present study, a scar/infarct model has been employed to investigate the contrast ratio performance of different native MRI mapping techniques (T1, T2, and T1ρ) under controlled conditions. Here, T1ρ provides the best results with an up to 12-times increased contrast ratio. Hence, T1ρ-mapping might be a very promising technique for scar imaging without the use of contrast agents.

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