Myocardial mapping techniques are known to provide new diagnostic possibilities for morphological and functional information including accurate tissue classification for several diseases. However, without the use of contrast agents, the differentiation between healthy and diseased tissue is hardly possible. In the present study, a scar/infarct model has been employed to investigate the contrast ratio performance of different native MRI mapping techniques (T1, T2, and T1ρ) under controlled conditions. Here, T1ρ provides the best results with an up to 12-times increased contrast ratio. Hence, T1ρ-mapping might be a very promising technique for scar imaging without the use of contrast agents.
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