Abstract #2264

Feasibility of Single Voxel Proton Spectroscopy of Pineal Gland at 7T

Ravi Prakash Reddy Nanga¹, Deepa Thakuri¹, Sanjeev Chawla¹, Dushyant Kumar¹, Abigail T. J. Cember¹, Hari Hariharan¹, Cynthia Neill Epperson², and Ravinder Reddy¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Psychiatry, University of Colorado, Aurora, CO, United States

Taurine is an important metabolite present in the pineal gland and is involved in the regulation of melatonin, which is plays a key role in regulation of sleep-wake cycle, in endocrine metabolism and in depression. However, there have been no known in vivo studies that measured neuro-metabolites in the pineal gland. In this study, for the first time, we explored the feasibility of single voxel proton spectroscopy from pineal gland in vivo in healthy human volunteers at 7.0T MRI.

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