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Abstract #2265

MRS reveals motor cortex basal GABA levels are correlated with handedness

Yasmin Geiger1 and Assaf Tal1

1Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel

Motor skills acquisition can manifest in changes in basal levels of metabolites in the motor cortex. We aim to study difference in metabolites basal levels in the ipsilateral and contralateral motor cortex using single voxel MRS. Our study showed significant difference only in basal GABA levels and the basal GABA/Glx ratio. This result should be kept in mind when interpreting or designing experiments studying the metabolic correlates of motor function.

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