Genomic Characterization of Medulloblastoma (MB) has recently identified 4 distinct molecular subgroups: Sonic Hedgehog (SHH), wingless (WNT), Group 3, and Group 4. These subgroups have shown different clinical behaviours and benefits to subgroup-specific treatments. We explored the feasibility of a new gradient-entropy radiomic feature, CoLlAGe, to distinguish molecular sub-types of MB on Gd-T1w MRI. Our results using multi-class comparison via one way ANOVA and post-hoc comparison showed significant differences in CoLlAGe features obtained across molecular sub-types. Our feasibility results suggest that the CoLlAGe features in different tumor regions observed on routine Gd-T1w MRI may potentially serve as surrogate markers to non-invasively characterize molecular sub-types of pediatric MB.