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Abstract #2616

The change of cerebral cortex in children with Tourette syndrome

Lei Kong1, Yue Liu1, Shao Meng Cao2, Lv Bin 2, and Yun Peng1

1Beijing Children's Hospital, Beijing, China, 2China Academy of Information and Communications Technology, Beijing, China

Tourette syndrome (TS) is a developmental neuropsychiatric disorder and is characterized by multiple motor and vocal tics. To understand the developmental cause of such changes, we investigated microstructural changes of cortical thickness , cortical sulcus, cortical curvature, and LGI in TS children by using sagittal three-dimensional T1-weighted image (3DT1WI) Magnetization. The TS children had the significant differences in cortical thickness, cortical sulcus, cortical curvature, and LGI compared with controls.

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