Abstract #2617

Altered cortical thickness relevance in the early blind, late blind during the critical developmental time

Ankeeta Ankeeta¹, S Senthil Kumaran², N R Jagannathan², and Rohit Saxena³

¹Neurology, All India Institute of Medical Sciences, New Delhi, India, ²NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, ³Rajendra Prasad Centre of Opthalmology, All India Institute of Medical Sciences, New Delhi, India

Visual impairment induces structural and functional modification in the visual cortex. There is significant modification observed between early blind subjects with thicker V1 compared to sighted controls, however late blind subjects with showed no significant differences in the V1 in age group of 6-12 years but there is differences observed between 13-19 years age range. Hence implicating the role of age of blindness onset may induce significant possessions on the expansion of cortical thickness of the V1.

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