Three-dimensional (3D) CUBE MRI for high-resolution vascular wall imaging can reveal the morphological characteristics of vessel wall. To investigate its feasibility in the diagnosis of central nervous system vasculitis, we applied the contrast-enhanced 3D T1-weighted CUBE imaging in the patients with vasculitis. We found significant alterations of the vessel wall imaging in signal-to-noise-ratio and contrast-to-noise-ratio before and after clinical treatment. With these, we can demonstrate that 3D CUBE MRI can effectively help to diagnose the central nervous system vasculitis and evaluate the treatment effect.
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