Abstract #2680

Investigation of Cerebral Small Vessel Disease induced Depression using Diffusion Kurtosis Imaging - A preliminary Region-specific Study

Kun Li¹, Dongtao Liu², Qiao Bu¹, Xiuqin Jia³, Rui Jia¹, Xiaojiao Pei¹, Yuchang Yan¹, Xiang Feng⁴, Qinglei Shi⁴, Zhenyu Pan¹, and Tao Jiang³

¹Department of Radiology, Beijing Chaoyang Hospital (Jingxi Campus), Capital Medical University, Beijing, China, ²Department of Neurology, Beijing Chaoyang Hospital (Jingxi Campus), Capital Medical University, Beijing, China, ³Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China, ⁴MR Scientific Marketing, Siemens Healthcare, Beijing, China

This abstract presents a preliminary study of cerebral small vessel disease induced depression using diffusion kurtosis imaging (DKI). Different DKI-derived parameters in specific brain structures were compared between depression and non-depression groups, as well as between anxiety and non-anxiety groups. The correlation between DTI- and DKI-derived parameters and clinical scores were also investigated.

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