Abstract #2693

Exploring White Matter Functional Networks at Rest in Boys with Attention Deficit/Hyperactivity Disorder Using Clustering Analysis and Tractography

Xuan Bu¹, Yingxue Gao¹, Hailong Li¹, Yanlin Wang¹, Lianqing Zhang¹, Xinyu Hu¹, Shi Tang¹, Lu Lu¹, Xiaoxiao Hu¹, Lanting Guo², and Xiaoqi Huang¹

¹Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu, China, ²Mental Health Center, Department of Psychiatry, West China Hospital of Sichuan University, Chengdu, Chile

In current study, we identified nine white matter functional networks and their relations to structural white matter fibers identified by DTI. Sensorimotor network and dorsal attention network, which show good spatial correspondence with specific anatomical tracts, present higher amplitude in ADHD. Our results uncover the altered intrinsic functional organization of white matter in ADHD, and indicate that changes in neural activity are encoded in BOLD variations within white matter.

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