Abstract #2806

Volumetric Brain Analysis in Older HIV-positive and -negative Subjects using 7T MRI

Mona A. Mohamed¹, Richard L. Skolasky², Andreia V. Faria¹, Peter B. Barker¹, and Ned C. Sacktor³

¹Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, United States, ²Orthopaedic Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, United States, ³Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, United States

Structural brain MRI is often performed to evaluate regional brain structure and atrophy in elderly subjects with cognitive impairment. In this study, 7T MRI was applied to 62 individuals 50 years and older (40 HIV+); an age-appropriate adult brain atlas was then used to segment and compare regional brain volumes as a function of age, HIV serostatus and neurocognitive classification.

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