Abstract #3435

Structural and Functional Characteristics of the Common Marmoset Brain Assessed Using Connectome Analysis

Yawara Haga^1,2,3,4, Junichi Hata^2,3,4, Fumiko Seki^2,3,4, Akiko Uematsu³, Mai Mizumura^1,3, Takaaki Kaneko^2,3, Hideyuki Okano^2,3, and Akira Furukawa¹

¹Radiological Sciences, Tokyo Metropolitan University Graduate School, Tokyo, Japan, ²Department of Physiology, Keio University School of Medicine, Tokyo, Japan, ³Laboratory for Marmoset Neural Architecture, Center for Brain Science, RIKEN, Wako, Japan, ⁴Live Imaging Center, Central Institute for Experimental Animals, Kawasaki, Japan

Connectome analysis with magnetic resonance imaging (MRI) is a non-invasive method and is an important approach for assessing brain networks and neurological diseases from a multilateral perspective. We examined the structural and functional characteristics of the common marmoset brain using structural and functional connectome analyses. For these connectome analyses, diffusion-weighted imaging and true-awake resting-state functional MRI (rsfMRI) were performed using a 9.4-T MRI scanner. The structural connectome analysis showed that the visual region had the most prominent structural characteristics in the marmoset brain. In addition, functional connectome analysis indicated that the functional connectome results were affected by the rsfMRI environment.

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