Abstract #3437

Readout segmented EPI based Relative apparent diffusion coefficient in early monitoring the treatment effect of low-intensity transcranial ultrasound: evaluation in a rat permanent occlusion model

Lanxiang Liu¹, Juan Du², Tao Zheng¹, Xuemei Wang¹, Huiling Yi¹, Shuang Wu¹, Qinglei Shi³, and Shuo Wu²

¹Department of Magnetic Resonance Imaging, Qinhuangdao Municipal No. 1 Hospital, Qinhuangdao, China, ²Graduate School of Hebei Medical University, Shijiazhuang, China, ³MR Scientific Marketing, Siemens Healthcare, Beijing, China

Acute ischemic stroke is a common and frequently occurring disease that severely harms human health and has high morbidity and mortality. Low-intensity transcranial ultrasound (LIPUS), due to its advantages of higher spatial resolution and greater penetration depth, has emerged as a new modality for noninvasive neuromodulation. This study indicated that the rADC based on readout segmented EPI sequence is a good indicator to evaluate the curative effect of LIPUS on acute cerebral infarction treatment.

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