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Abstract #3449

Reduced field-of-view Diffusion-weighted imaging at 3T for Evaluating Allograft Fibrosis After Kidney Transplantation: A Preliminary Study

Yuan Meng Yu1, Long Jiang Zhang2, and Yong Zhang3

1Department of Medical Imaging, Jinling Hospital, Nanjing Clinical School, Southern Medical University, Nanjing, China, China, 2Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China, Nanjing, China, China, 3GE Healthcare, Advanced Application, Shangha, China, Shangha, China, China

The extent of renal allograft fibrosis is a critical predictor of adverse allograft outcome. This institutional review board approved study included 109 renal transplantation recipients receiving 3 T multi-b reduced field-of-view intravoxel incoherent motion diffusion-weighted imaging (rFOV IVIM-DWI) examinations. The purpose of the present study is exploring the diagnostic value of evaluating allograft fibrosis with IVIM-DWI. In the present study, we have found that there is downward trend of ADCT and ADCD with the development of kidney fibrosis and both of them had good diagnostic efficiency in the distinguish fibrosis extent.

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