Abstract #3501

Motion-Robust and Distortion-Corrected Diffusion MR Imaging of the Liver with Optimized Motion-Compensated Waveforms and Multi-shot EPI acquisition

Yuxin Zhang^1,2, Ruiqi Geng^1,2, Arnaud Guidon³, James H Holmes², and Diego Hernando^1,2

¹Medical Physics, University of Wisconsin Madison, madison, WI, United States, ²Radiology, University of Wisconsin Madison, madison, WI, United States, ³Applications and Workflow, GE Healthcare, Boston, MA, United States

Conventional liver diffusion MRI acquisitions suffer from several challenges including low spatial resolution, B0-induced distortions, and elastic motion-induced signal voids. In this work, motion-robust and distortion-corrected liver diffusion-weighted imaging (DWI) was enabled by combining optimized motion compensated diffusion waveforms with multi-shot EPI acquisitions. Diffusion-weighted images of healthy volunteers were acquired to evaluate the effect of motion compensation and distortion correction. Preliminary results demonstrate the feasibility of the proposed approach, including reduced ADC bias in the left lobe (due to the motion-robust waveforms) and reduced distortion (due to the multi-shot acquisition) compared to conventional liver DWI.

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