Abstract #3571

Dependence of harmonic power on b-value for fiber ball imaging: comparison of theory and experiment

Hunter G. Moss^1,2, Emilie T. McKinnon^1,2,3, Joseph A. Helpern^1,2, and Jens H. Jensen^1,2

¹Department of Neuroscience, Medical University of South Carolina, Charleston, SC, United States, ²Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, United States, ³Department of Neurology, Medical University of South Carolina, Charleston, SC, United States

Fiber ball imaging (FBI) is a recently proposed diffusion MRI (dMRI) method for estimating fiber orientation density functions together with specific microstructural parameters in white matter. The theory underlying FBI predicts the b-value dependence for the dMRI harmonic power of any given degree as long as the b-value is sufficiently large. Good agreement between theory and experiment has been previously demonstrated for the zero-degree harmonic power. Here the predicted functional forms for higher degree harmonics are shown to also agree well with experimental measurements, providing additional support for the validity of FBI.

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