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Abstract #3688

Altered bilateral functional connectivity in rat brain under isoflurane and medetomidine anesthesia

Ting Yin1, Rolf Gruetter1, and Ileana Ozana Jelescu1

1CIBM-AIT, École polytechnique fédérale de Lausanne, Lausanne, Switzerland

Anesthetic agents are commonly used in rodent resting-state functional MRI. When anesthetized under different agents, brain functional connectivity can be altered. It has been shown that after isoflurane initiation, brain connectivity measured under medetomidine was extensively affected in a time-dependent manner. Here, we further compare the difference of resting-state networks detected under isoflurane and medetomidine anesthesia.

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