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Abstract #3724

Cerebral blood flow affected by the order of functional tasks

Yaoyu Zhang1,2 and Jia-Hong Gao2

1Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, 2Center for MRI Research, Peking University, Beijing, China

This study investigates the order effect of functional task-induced CBF responses. ASL sequence was implemented to quantify CBF responses to the same task but in paradigms of different task orders in both the motor and visual cortices. Results of the study show an order effect in which that the greater the work load of the prior task, the greater influence it can exert on the CBF response of the posterior task. This study emphasizes the importance of the randomized task design and gives insight on underlying task-induced CBF response mechanisms.

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