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Abstract #3939

Inter-site repeatability of motor-visual task fMRI responses at 7 Tesla

Ian D Driver1, Olivier Mougin2, William T Clarke3, Catarina Rua4, Andrew T Morgan5, Adrian Carpenter4, Keith Muir5, David Porter5, Christopher T Rodgers4, Stuart Clare3, Susan T Francis2, Richard Bowtell2, and Richard G Wise1

1Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, United Kingdom, 2Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 3Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 4Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, 5Imaging Centre of Excellence, University of Glasgow, Glasgow, United Kingdom

This work studies cross-site variability in 7 Tesla task fMRI measurements, collected as part of a “travelling heads” study. Participants were scanned at the five human UK 7 Tesla MRI sites, and results are presented from four of these sites. A motor-visual task was performed at each site with acquisitions matched as closely as possible. Despite some apparent differences in tSNR , we demonstrate that it is possible to achieve good agreement across sites. The %BOLD coefficient of variation of 0.1-0.2 across sites was similar to the within-site ranges. This work sets the foundation for multi-site 7 Tesla clinical trials.

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