Abstract #3996

Feasibility of Partial 3D GluCEST in Healthy Human Adults at 7.0T

Ravi Prakash Reddy Nanga¹, Abigail T. J. Cember¹, Deepa Thakuri¹, Dushyant Kumar¹, Neil E. Wilson¹, Hari Hariharan¹, Mark Elliott¹, Cynthia Neill Epperson², and Ravinder Reddy¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Psychiatry, University of Colorado, Aurora, CO, United States

GluCEST imaging at 7.0T has been promising in clinical applications as demonstrated in small subset of temporal lobe epilepsy subjects and in early psychosis. However, these studies employed 2D GluCEST limiting to single slice and limited coverage of anatomy of interest. Here, we tried to implement the partial 3D GluCEST in order to capture the glutamate contrast from the entire hippocampus as opposed to single slice in the same amount of time.

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