Septal wall thickness measurements using hyperpolarized xenon-129 MRI are sensitive to inflammatory or fibrotic pathologies but currently require multi-second breath-holds. We investigated the feasibility of sampling the recovery of the xenon dissolved-phase magnetization in the lung parenchyma in real time using a rapid 1D acquisition technique combined with periodic saturation of the xenon dissolved-phase magnetization, allowing us to extract the septal wall thickness during short breath holds or even in free-breathing rabbits. Our measurements indicate that the correlation between the derived septal wall thickness and the respiratory cycle are low enough to obtain consistent wall-thickness measurements in free-breathing, non-cooperative subjects.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords