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Abstract #4279

An Optimized GRASE Sequence for Preclinical and Human Hyperpolarized 13C Imaging

Shuyu Tang1,2, Jeremy Gordon1, Peng Cao1, Robert Bok1, Daniel Vigneron1, and Peder Larson1

1University of California at San Francisco, San Francisco, CA, United States, 2University of California at Berkeley, Berkeley, CA, United States

An optimized GRASE sequence was developed for dynamic hyperpolarized 13C Imaging and demonstrated the feasibility for human brain research. The multi-echo signal can either be used to encode a 3D volume or as a 2D multi-echo approach to increase SNR or estimate T2. Varied crusher gradients were investigated to reduce the loss of longitudinal hyperpolarized 13C magnetization.

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