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Abstract #4298

Fast acquisition of hyperpolarized MR with Multi-echo EPI

Kofi Deh1, Kristin L Granlund1, and Kayvan R Keshari1,2

1Radiology & Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 2Weill Cornell Medical College, New York, NY, United States

An EPI acquisition can efficiently acquire data, allowing multiple images to be acquired before the transverse signal decays due to T2*. These images (acquired at different echo times) can be reconstructed into images of individual species, as with Dixon or IDEAL. This approach can be used to efficiently acquire hyperpolarized data by limiting the number of excitations to preserve longitudinal magnetization for subsequent time points or enabling the use of larger flip angles for higher SNR. In this abstract, we demonstrate the feasibility of this approach with thermal phantoms (acetate, alanine, and urea) and with hyperpolarized phantoms (pyruvate and urea).

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