Meeting Banner
Abstract #4305

Distinguishing metabolic signals of liver tumors from surrounding liver cells using hyperpolarized 13C MRI and Gadoxetate

Shubhangi Agarwal1,2, Jeremy Gordon1, Natalie Korn1, Robert A Bok1, Cornelius von Morze1,2, Daniel B Vigneron1,2, John Kurhanewicz1, and Michael A Ohliger1,2

11Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, United States, 2Liver Center, University of California, San Francisco, CA, United States

Hyperpolarized (HP) 13C MRI is a new technique that can assess the metabolic pathways in a variety of tumors. In this study, we show the ability of a gadolinium-based contrast agent (gadoxetate) to selectively suppress the HP metabolic signal arising from normal hepatocytes by altering the relaxation rates of metabolites 13C pyruvate and 13C lactate in order to evaluate the metabolic profile of tumors within the liver.

This abstract and the presentation materials are available to members only; a login is required.

Join Here